What is the cancer stem cell theory? What are cancer stem cells and transit amplifying cells? How do they differ?

What is the cancer stem cell theory?

What are cancer stem cells and transit amplifying cells? How do they differ?

What are the different barriers to metastasis. Which are easy and which are harder for cancer cells to overcome?

What is the Bcr-Abl fusion gene and what is its role in myelogenous leukemia?

Gleevec, the drug used to treat myelogenous leukemia?

What are the different chemotherapy strategies (i.e. multi-drug vs. sequential treatments)?

What is the ‘seed-and-soil’ hypothesis?

What is contralateral metastasis?

Explain metastasis of breast cancer to the bone and osteolytic metastasis?